The Boxing competition at the 2010 Central American and Caribbean Games was held in Mayagüez, Puerto Rico. The tournament was scheduled from 23–31 July at the Coliseo Rafael A. Mangual in Mayagüez.
| Event | Gold | Silver | Bronze |
|---|---|---|---|
| Light −Fly 48kg | Angel Acosta (PUR) | Alvaro Vargas (GUA) | David Jimenez (CRC) Gilberto Pedroza (PAN) |
| Fly −51kg | Jonathan Gonzalez (PUR) | Ceiber Avila (COL) | Braulio Avila (MEX) Dexter Jordan (GUY) |
| Bantam −54kg | Camilo Pérez (PUR) | Oscar Negrete (COL) | Alexander Espinoza (NCA) Jorge Nuñez (DOM) |
| Feather 56kg | Oscar Valdez (MEX) | Juan Reyes (GUA) | Roberto Navarro (DOM) Ray Sandiford (GUY) |
| Light −60kg | José Pedraza (PUR) | Cesar Villarraga (COL) | Joselito Aguirre (GUA) Wellintong Arias (DOM) |
| Light Welter −64kg | Valentino Knowles (BAH) | Luis Romero (VEN) | Ricardo Garcia Tejada (DOM) Juan Pablo Romero (MEX) |
| Welter −69kg | Christian Peguero (PUR) | Oscar Molina (MEX) | Juan Carlos Abreu (DOM) Aaron Prince (TRI) |
| Middle −75kg | Enrique Collazo (PUR) | Felix Valera (DOM) | Jose Bernal (ESA) Jovan Young (JAM) |
| Light Heavy −81kg | Jeysson Monroy (COL) | Andrew Fermin (TRI) | Israel Duffus (PAN) Francisco Ortega (MEX) |
| Heavy −91kg | Julio Deivis (COL) | Joel Cabrera (DOM) | Anderson Emmanuel (BAR) Ismael Lewitt (NCA) |
| Super Heavy +91kg | Gerardo Bisbal (PUR) | Gilton Zimmermann (AHO) | Torig Hagg (TRI) José Payares (VEN) |
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